Anti-Integrin beta-3 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-Integrin beta-3 Rabbit Polyclonal Antibody

Anti-Integrin beta-3 Rabbit Polyclonal Antibody

Anti-Integrin beta-3 Rabbit Polyclonal Antibody

Anti-Integrin beta-3 Rabbit Polyclonal Antibody

18309-1-AP-150UL

10089-022EA 402 USD

10089-022

Anti-Integrin beta-3 Rabbit Polyclonal Antibody

Antibodies

CD61, also named as CD61,ITGB3 and GPIIIa, is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. CD61 recognize the sequence R-G-D in a wide array of ligands and the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation CD61 brings about platelet/platelet interaction through binding of soluble fibrinogen which leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Western Blot: Human Placenta Tissue, 1:500-1:5000; IHC: Human Testis, 1:20-1:200

Type: Primary
Antigen: Integrin beta-3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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