Anti-Pinin Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

Anti-Pinin Rabbit Polyclonal Antibody

18266-1-AP-150UL

10092-340EA 402 USD

10092-340

Anti-Pinin Rabbit Polyclonal Antibody

Antibodies

PNN, also named as DRS or 140 kDa nuclear and cell adhesion-related phosphoprotein, is a 717 amino acid protein, which belongs to the pinin family. PNN localizes in the plasma membrane and is expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon, heart, epidermis, esophagus, brain and smooth and skeletal muscle. PNN is expressed strongly in melanoma metastasis lesions and advanced primary tumors. PNN as a transcriptional activator binds to the E-box 1 core sequence of the E-cadherin promoter gene. PNN is involved in the establishment and maintenance of epithelia cell-cell adhesion. PNN is a potential tumor suppressor for renal cell carcinoma. The calculated molecular weight of PNN is 82 kDa (native form), but the post-modified protein is 140 kDa (phospho form of isoform 1).

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human Kidney Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100

Type: Primary
Antigen: Pinin
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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