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Anti-IkB alpha Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

Anti-IkB alpha Rabbit Polyclonal Antibody

18220-1-AP-150UL

10081-558EA 402 USD

10081-558

Anti-IkB alpha Rabbit Polyclonal Antibody

Antibodies

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA, synonyms: IKBA, MAD-3, NFKBI). NFKB1 or NFKB2 is bound to REL, RELA , or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.

Western Blot: HL-60 Cells, 1:500-1:5000; IHC: Human Liver Tissue, 1:20-1:200; IP: HeLa Cells, 1:200-1:2000

Type: Primary
Antigen: IkB alpha
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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