Anti-HEPACAM Rabbit Polyclonal Antibody

Supplier: Proteintech
10088-160EA 402 USD
Anti-HEPACAM Rabbit Polyclonal Antibody
HepaCAM (hepatocyte cell adhesion molecule), also known as GlialCAM, is a single-pass type I membrane glycoprotein of 416 amino acids. It displays a typical structure of immunoglobulin (Ig)-like adhesion molecules including two extracellular Ig-like domains, a transmembrane segment, and a cytoplasmic tail. It has been shown that hepaCAM forms a cis-homodimer on the cell surface, and modulates cell-matrix interaction. It is predominantly expressed in the CNS glial cells. Defects in HEPACAM gene are the cause of megalencephalic leukoencephalopathy with subcortical cysts type 2A (MLC2A). HEPACAM has also been suggested as a tumor suppressor gene.

Western Blot: Mouse Brain Tissue, 1:200-1:2000; IHC: Human Liver Tissue, 1:20-1:200; IF: MCF-7 Cells, 1:10-1:100

Type: Primary
Antigen: HEPACAM
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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