Anti-TRAF3 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-TRAF3 Rabbit Polyclonal Antibody

Anti-TRAF3 Rabbit Polyclonal Antibody

Anti-TRAF3 Rabbit Polyclonal Antibody

Anti-TRAF3 Rabbit Polyclonal Antibody

Anti-TRAF3 Rabbit Polyclonal Antibody

Anti-TRAF3 Rabbit Polyclonal Antibody

18099-1-AP-150UL

10095-712EA 537.7 USD

10095-712

Anti-TRAF3 Rabbit Polyclonal Antibody

Antibodies

TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.

Western Blot: Raji Cells, 1:200-1:2000; IP: Raji Cells, 1:200-1:2000

Type: Primary
Antigen: TRAF3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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