Anti-UGT8 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-UGT8 Rabbit Polyclonal Antibody

Anti-UGT8 Rabbit Polyclonal Antibody

Anti-UGT8 Rabbit Polyclonal Antibody

Anti-UGT8 Rabbit Polyclonal Antibody

Anti-UGT8 Rabbit Polyclonal Antibody

Anti-UGT8 Rabbit Polyclonal Antibody

17982-1-AP-150UL

10096-762EA 402 USD

10096-762

Anti-UGT8 Rabbit Polyclonal Antibody

Antibodies

UGT8, also known as galacotosylceramide synthase or CGT (ceramide galactosyltransferase), is a key enzyme for galacotosylceramide (GalCer) biosynthesis. It is an ER transmembrane protein and has limited tissue distribution, with predominance in Schwann cells, oligodendrocytes, kidneys, testes, and intestine. UGT8 is highly enriched in myelin in the central nervous system. Its expression levels are strongly associated with histological typing in human oligodendrogliomas and astrocytomas; can be used as molecular marker to distinguish these tumors. Higher UGT8 levels had also been linked to metastatic properties of cancer cells. This antibody specifically recognizes the endogenous UGT8.

Western Blot:rat Brain Tissue, 1:500-1:5000; IHC: Human Brain Tissue, 1:20-1:200

Type: Primary
Antigen: UGT8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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