Anti-UPA Rabbit Polyclonal Antibody

Supplier: Proteintech
10096-798EA 402 USD
Anti-UPA Rabbit Polyclonal Antibody
PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1 (PAI-1), which is stored in the extracellular matrix bound to vitronectin.It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder (QPD).

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human skin Tissue, 1:20-1:200

Type: Primary
Antigen: UPA
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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