Anti-CSK Rabbit Polyclonal Antibody

Supplier: Proteintech
10084-626EA 402 USD
Anti-CSK Rabbit Polyclonal Antibody
CSK(Tyrosine-protein kinase CSK) is also named as C-Src kinase, protein-tyrosine kinase CYL and belongs to the protein kinase superfamily. Csk is a non-receptor tyrosine kinase with a molecular mass of 50 kDa. It contains the SH3 and SH2 domains in its N-terminus and a kinase domain in its C-terminus. It negatively regulates the kinase activity of SFKs and plays an important role in physiological functions via signaling pathways for cell proliferation, differentiation, adhesion, and migration. Csk may play a role in tumor suppression by inhibiting the oncogenic activity of SFKs. Indeed, overexpression of Csk can inhibit tumor growth of human colon cancer cells. This protein can be autophosphorylated.

Western Blot: HL-60 Cells, 1:200-1:2000; IHC: Human lung Tissue, 1:20-1:200; IF:SH-SY5Y Cells, 1:10-1:100

Type: Primary
Antigen: CSK
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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