Anti-P5CS Rabbit Polyclonal Antibody

Supplier: Proteintech
10091-696EA 402 USD
Anti-P5CS Rabbit Polyclonal Antibody
Delta 1-pyrroline-5-carboxylate synthetase (P5CS), also named as GSAS, P5CS, PYCS, catalyzes the ATP and the NAD(P)H-dependent conversion of L-glutamate to glutamic gamma-semialdehyde (GSA) which is the metabolic precursor for proline biosynthesis. This protein includes 2 domains: glutamate 5-kinase and gamma-glutamyl phosphate reductase. In the N-terminal section, it belongs to the glutamate 5-kinase family and in the C-terminal section, it belongs to the gamma-glutamyl phosphate reductase family. Defects in ALDH18A1 are the cause of cutis laxa, autosomal recessive, type 3A (ARCL3A). It has 2 isoforms produced by alternative splicing.

Western Blot: MCF7 Cells, 1:500-1:5000; IP: Mouse Brain Tissue, 1:200-1:2000

Type: Primary
Antigen: P5CS
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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