ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation . ARL13B can be used to mark the cilia .
Western Blot: Mouse Liver Tissue, 1:500-1:5000; IHC: Human Liver Tissue, 1:20-1:200; IF:NIH3T3 Cells, 1:10-1:100; IP:L02 Cells, 1:500-1:5000
Type: Primary
Antigen: ARL13B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat