Anti-RIPK3 Rabbit Polyclonal Antibody

Supplier: Proteintech
10093-696EA 524.34 USD
Anti-RIPK3 Rabbit Polyclonal Antibody
RIPK3,also named as RIP3, a Ser/Thr kinase of RIP (Receptor Interacting Protein) family, is recruited to the TNFR1 signaling complex through RIP and has been shown to mediate apoptosis induction and NF-κB activation. RIPK3 is a nucleocytoplasmic shuttling protein and its unconventional nuclear localization signal (NLS, 442–472 aa) is sufficient to trigger apoptosis in the nucleus. It has 3 isoforms produced by alternative splicing. RIPK3 might form a homodimer within cells, and its apoptotic activity may not be required for this dimerization.

IP:SW 1990 Cells, 1:200-1:1000; Western Blot:Jurkat Cells, 1:200-1:1000

Type: Primary
Antigen: RIPK3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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