Anti-IRS1 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

Anti-IRS1 Rabbit Polyclonal Antibody

17509-1-AP-150UL

10088-984EA 402 USD

10088-984

Anti-IRS1 Rabbit Polyclonal Antibody

Antibodies

Insulin receptor substrate 1 (IRS1) was the first cloned and characterized member of the IRS family which are involved in insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) signaling. IRS1 is phosphorylated by insulin receptor tyrosine kinase and is involved in various cellular processes including DNA repair fidelity, transcriptional activity, and cell growth can support tumor development and progression. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. IRS1 has a predicted molecular weight of 132 kDa, however, as a result of its extensive serine phosphorylation it separates on a SDS gel as a band of approximately 160-185 kDa.

Western Blot:A549 Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200; IP:A549 Cells, 1:500-1:5000

Type: Primary
Antigen: IRS1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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