Anti-OGDHL Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-OGDHL Rabbit Polyclonal Antibody

Anti-OGDHL Rabbit Polyclonal Antibody

Anti-OGDHL Rabbit Polyclonal Antibody

Anti-OGDHL Rabbit Polyclonal Antibody

Anti-OGDHL Rabbit Polyclonal Antibody

Anti-OGDHL Rabbit Polyclonal Antibody

17110-1-AP-150UL

10091-558EA 402 USD

10091-558

Anti-OGDHL Rabbit Polyclonal Antibody

Antibodies

OGDHL(oxoglutarate dehydrogenase-like) is also named as KGDE1KL, FLJ10851, KIAA1290 and belongs to the alpha-ketoglutarate dehydrogenase family. OGDHL is one of the rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associated with neuro-degeneration and it is localized only in the mitochondrial fraction and not in the cytosolic or nuclear fractions. OGDHL negatively regulates cell proliferation by inducing apoptosis in cervical cancer cells. It may thus participate in brain-specific control of 2-oxoglutarate distribution between energy production and synthesis of the neurotransmitter glutamate. It has 3 isoforms(114 kDa, 108 kDa, 91 kDa) produced by alternative splicing.

Western Blot: Mouse Kidney Tissue, 1:500-1:5000; IHC: Human Brain Tissue, 1:20-1:200

Type: Primary
Antigen: OGDHL
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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