Anti-SPHK2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10095-092EA 537.7 USD
Anti-SPHK2 Rabbit Polyclonal Antibody
SPHK2(Sphingosine kinase 2) is also named as SK2,SPK2 and catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. SPHK2 associates with HDAC1 and HDAC2 in repressor complexes and is selectively enriched at the promoters of the genes encoding the cyclin-dependent kinase inhibitor p21 or the transcriptional regulator c-fos, where it enhanced local histone H3 acetylation and transcription.SphK2 is a ~66kDa protein that is most abundantly expressed in the liver and heart.

Western Blot: Mouse cerebellum Tissue, 1:200-1:2000; IHC: Human Kidney Tissue, 1:20-1:200

Type: Primary
Antigen: SPHK2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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