Anti-NEDD8 Rabbit Polyclonal Antibody

Supplier: Proteintech
10091-012EA 402 USD
Anti-NEDD8 Rabbit Polyclonal Antibody
NEDD8 (neural precursor cell-expressed developmentally down-regulated gene 8) is a small ubiquitin-like protein that shares 60% sequence identity and 80% homology with ubiquitin . NEDD8 is conjugated to substrate proteins in a process known as neddylation. NEDD8 forms a thioester bond with APPBP1-Uba3, the E1 enzyme. Activated NEDD8 then transfers to Ubc12, the E2 enzyme . Ultimately, E2 loaded with NEDD8 binds a substrate protein lysine residue and forms an isopeptide bond by E3 ligase .

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200

Type: Primary
Antigen: NEDD8
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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