Anti-CD40L Rabbit Polyclonal Antibody

Supplier: Proteintech
16668-1-AP-150UL
10084-280EA 402 USD
10084-280
Anti-CD40L Rabbit Polyclonal Antibody
Antibodies
The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33-kd transmembrane homologue or 18-kd soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and on a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis.

Western Blot: Mouse small intestine Tissue, 1:500-1:5000; IHC: Human spleen Tissue, 1:20-1:200

Type: Primary
Antigen: CD40L
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:
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