Anti-VIL1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10096-976EA 402 USD
Anti-VIL1 Rabbit Polyclonal Antibody
Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.

Western Blot: Mouse Kidney Tissue, 1:200-1:2000; IHC: Human small intestine Tissue, 1:20-1:200; IF:COLO 320 Cells, 1:20-1:200

Type: Primary
Antigen: VIL1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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