The cell division cycle 25 (CDC25) family of proteins are highly conserved dual specificity phosphatases that activate cyclin-dependent kinase (CDK) complexes, which in turn regulate progression through the cell division cycle. CDC25C(cell division cycle 25 homolog C) is one of the 3 isoforms of CDC25 in mammalian cells. It is present in the cytoplasm of asynchronously growing human cells. And it may be phosphorylated by its own substrate, an active cdc2-cyclin B complex, to create an autoactivation loop. It can be hyperphosphorylated to get the active form of 70 kDa.
Western Blot:K-562 Cells, 1:200-1:2000
Type: Primary
Antigen: CDC25C
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: