Anti-A1AT Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

Anti-A1AT Rabbit Polyclonal Antibody

16382-1-AP-150UL

10094-350EA 402 USD

10094-350

Anti-A1AT Rabbit Polyclonal Antibody

Antibodies

SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT), which is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes, with smaller amountssynthesized by intestinal epithelial cells, neutrophils, pulmonary alveolar cells and macrophages. AAT is the most abundant, endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation, fibrinolysis, complement activation, apoptosis, reproduction, tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.

IHC: Human Liver Tissue, 1:20-1:200; Western Blot: Mouse Kidney Tissue, 1:500-1:5000

Type: Primary
Antigen: A1AT
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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