Anti-MKS1 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

Anti-MKS1 Rabbit Polyclonal Antibody

16206-1-AP-150UL

10090-258EA 402 USD

10090-258

Anti-MKS1 Rabbit Polyclonal Antibody

Antibodies

MKS1 (Meckel syndrome type 1 protein) is a 559-amino acid protein that contains a conserved B9 domain. It is a component of a large protein complex which localizes to the ciliary transition zone and regulates mammalian ciliogenesis and ciliary membrane composition . MKS1 is required for ciliary structure and function, and is involved in centrosome migration to the apical cell surface during early ciliogenesis . Broad tissue expression of the MKS1 gene has been reported . Defects in MKS1 are the cause of Meckel syndrome type 1 (MKS1), an autosomal recessive lethal malformation syndrome characterized by renal cystic dysplasia, central nervous system malformations, and hepatic developmental defects . In addition, defects in MKS1 are also the cause of Bardet-Biedl syndrome type 13 (BBS13) .

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Liver cancer Tissue, 1:20-1:200; IF: HTERT-RPE1 Cells and Mouse Embryonic fibroblasts, 1:20-1:200; IP: HEK-293 Cells, 1:500-1:5000

Type: Primary
Antigen: MKS1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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