S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells, and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis, and chemoresistance. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200
Type: Primary
Antigen: S100 A4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat