Anti-PLA2G12A Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-PLA2G12A Rabbit Polyclonal Antibody

Anti-PLA2G12A Rabbit Polyclonal Antibody

Anti-PLA2G12A Rabbit Polyclonal Antibody

Anti-PLA2G12A Rabbit Polyclonal Antibody

Anti-PLA2G12A Rabbit Polyclonal Antibody

Anti-PLA2G12A Rabbit Polyclonal Antibody

16009-1-AP-150UL

10092-412EA 402 USD

10092-412

Anti-PLA2G12A Rabbit Polyclonal Antibody

Antibodies

PLA2G12A (or PLA2G12) gene encodes group XII secreted phospholipase A2 (sPLA2) which catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Cellular arachidonate (AA) release and prostaglandin (PG) production is regulated by sPLA(2)s, groups III and XII. Group XII sPLA2 have relatively low specific activity and are structurally and functionally distinct from other sPLA2s. Cells transfected with group XII sPLA(2) exhibited abnormal morphology, suggesting a unique functional aspect of this enzyme. Role of sPLA2s as potential tumour biomarkers and therapeutic targets for various cancers have been reported.

Western Blot: Mouse Skeletal Muscle Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200

Type: Primary
Antigen: PLA2G12A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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