Anti-IFT25 Rabbit Polyclonal Antibody

Supplier: Proteintech
10088-522EA 402 USD
Anti-IFT25 Rabbit Polyclonal Antibody
HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.

Western Blot: HeLa Cells, 1:500-1:5000; IF: HTERT-RPE1 Cells, 1:20-1:200

Type: Primary
Antigen: IFT25
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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