Anti-RNASEH1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10093-768EA 537.7 USD
Anti-RNASEH1 Rabbit Polyclonal Antibody
Ribonucleases H are enzymes that cleave the RNA of RNA/DNA hybrids that form during replication and repair and which could lead to DNA instability if they were not processed. Eukaryotic RNases H are larger and more complex than their prokaryotic counterparts . Eukaryotic RNase H1 has acquired a Hybrid Binding Domain that confers processivity and affinity for the substrate. Because of its essential role and its similarities in structure and enzymatic mechanism to the RNase H of HIV reverse transcriptase, RNASEH1 has been implicated in mitochondrial DNA replication during mouse development .

Western Blot: HeLa Cells, 1:500-1:5000

Type: Primary
Antigen: RNASEH1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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