Anti-PPARA Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-PPARA Rabbit Polyclonal Antibody

Anti-PPARA Rabbit Polyclonal Antibody

Anti-PPARA Rabbit Polyclonal Antibody

Anti-PPARA Rabbit Polyclonal Antibody

15540-1-AP-150UL

10092-628EA 402 USD

10092-628

Anti-PPARA Rabbit Polyclonal Antibody

Antibodies

Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that belongs to the PPAR nuclear receptor superfamily. PPARA is essential in the modulation of lipid transport and metabolism, mainly through activating mitochondrial and peroxisomal fatty acid β-oxidation pathways. In addition, PPARA seems to decrease inflammation mainly through direct interaction with NF-κB, causing inhibition of its signaling pathway or reducing the activated levels of NF-κB and subsequent inflammation. Furthermore, PPARA was implicated in the attenuation of oxidative stress in alcoholic liver disease when treated with polyenephosphatidylcholine through downregulation of ROS-generating enzymes such as ethanol-inducible cytochrome P450 2E1 (CYP2E1), acyl-CoA oxidase, and NADPH oxidase.

Western Blot:U-937 Cells, 1:200-1:1000; IHC: Human Skeletal Muscle Tissue, 1:20-1:200

Type: Primary
Antigen: PPARA
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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