Anti-KISS1R Rabbit Polyclonal Antibody

Supplier: Proteintech
10089-290EA 402 USD
Anti-KISS1R Rabbit Polyclonal Antibody
receptor for metastin (kisspeptin-54, 13, 14, 10), C- terminally amidated peptides of KiSS-1. KiSS-1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some other carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Western Blot:SH-SY5Y Cells, 1:500-1:5000; IF: MCF-7, 1:10-1:100

Type: Primary
Antigen: KISS1R
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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