Anti-SPARC Rabbit Polyclonal Antibody

Supplier: Proteintech
10095-062EA 402 USD
Anti-SPARC Rabbit Polyclonal Antibody
SPARC, also known as ON (Osteonectin) or BM-40 (Basement-membrane protein 40), is a 43-kDa extracellular glycoprotein that belongs to a group of matricellular proteins defined as secreted components that do not contribute directly to the formation of structural elements but serve to modulate cell-matrix interactions and cellular functions . SPARC is expressed at high levels in bone tissue, is distributed widely in many other tissues and cell types, and is associated generally with tissues undergoing morphogenesis, remodeling and wound repair . It elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix . Altered expression of SPARC has been reported in a variety of cancers, which include breast, ovarian, colorectal, and pancreatic cancer as well as melanoma and glioblastomas .

Western Blot: Human Placenta Tissue, 1:1000-1:10000; IHC: Human Stomach cancer, 1:20-1:200

Type: Primary
Antigen: SPARC
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Pig
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