Anti-NCK1 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

Anti-NCK1 Rabbit Polyclonal Antibody

15247-1-AP-150UL

10090-866EA 402 USD

10090-866

Anti-NCK1 Rabbit Polyclonal Antibody

Antibodies

NCK family adaptor proteins function to couple tyrosine phosphorylation signals to regulate actin cytoskeletal reorganization that leads to cell motility. Cytoplasmic protein NCK1 (or NCK alpha) is an adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 binds a number of intracellular proteins and influences various signaling pathways including GTPase-activating protein of Ras (RasGAP), which is responsible for the down-regulation of Ras. NCK1 is recently reported to regulate the UPR, which secondary to obesity impairs glucose homeostasis and insulin actions.

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human breast cancer, 1:20-1:200; IF: Hela, 1:10-1:100

Type: Primary
Antigen: NCK1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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