CD98 is a cell-surface heterodimer consisting of a heavy chain (CD98hc) and a light chain. CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.. This protein has 4 isoforms produced by alternative splicing.
Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human Testis Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; FC: HepG2 Cells, N/A
Type: Primary
Antigen: CD98
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: