Anti-CRLS1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-194EA 402 USD
Anti-CRLS1 Rabbit Polyclonal Antibody
Cardiolipin (CL) is a mitochondrial specific double negatively charged phospholipid which is intricately involved in regulating bioenergetic efficiency. In eukaryotes, CL is synthesized by cardiolipin synthase (CRLS1 or CLS1) which catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form CL and glycerol. Recently it has been reported that transgenic expression of CRLS1 accelerates cardiolipin remodeling, improves mitochondrial function, modulates mitochondrial signaling, and attenuates mitochondrial dysfunction during diabetes, thereby identifying CRLS1 as a novel therapeutic target to attenuate mitochondrial dysfunction in diabetic myocardium.

IHC: Human Liver cancer, 1:20-1:200

Type: Primary
Antigen: CRLS1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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