Anti-ATF2 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-ATF2 Rabbit Polyclonal Antibody

Anti-ATF2 Rabbit Polyclonal Antibody

14834-1-AP-150UL

10083-228EA 402 USD

10083-228

Anti-ATF2 Rabbit Polyclonal Antibody

Antibodies

ATF2, also named as CREB2 and CREBP1, contains one bZIP domain and one C2H2-type zinc finger. It belongs to the bZIP family. ATF2 binds to the cAMP-responsive element(CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. It is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. ATF2 binds DNA as a dimer and can form a homodimer in the absence of DNA. It binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity. This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human ATF2.

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200

Type: Primary
Antigen: ATF2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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