Anti-SF3B3 Rabbit Polyclonal Antibody

Supplier: Proteintech
10094-438EA 402 USD
Anti-SF3B3 Rabbit Polyclonal Antibody
Introns are removed from nuclear pre-mRNA in 2-step transesterification reactions. Splicing occured in a large ribonucleoprotein particle, called the spliceosome. Spliceosomal intermediate complexes form on pre-mRNA in the order E, A, B, and C, with the catalytic reactions occurring in complex C. U2 small nuclear ribonucleoproteins are one of the proteins essential for spliceosome assembly and mRNA splicing. Functional U2 snRNP is composed of a 12S unit and 2 splicing factors, SF3A, which is composed of 3 proteins, and SF3B, which conposed of 4 proteins. SF3B3 is one of SF3B, and it's required for 'A' complex assembly formed by the stable binding of U2 snRNP to the brachpoint sequence(BPS) in pre-mRNA.

Western Blot: HeLa Cells, 1:1000-1:10000; IHC: Human gliomas Tissue, 1:20-1:200; IF: Hela Cells, 1:20-1:200

Type: Primary
Antigen: SF3B3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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