TOMM70A (or TOM70) is a mitochondrial import receptor responsible for the import of cytosol synthesized precursor proteins into the mitochondria. Tom70 is a member of the tetratricopeptide repeat (TPR) co-chaperone family and contains a conserved TPR clamp domain for interaction with Hsc70 and Hsp90. Recently overexpression of TOM70 has been linked to chemoresistance to drugs in breast cancer cell lines. It is also believed that Tom70 is significantly associated with breast cancer relapse and may predict the recurrence of ovarian cancer.
Western Blot: Mouse Liver Tissue, 1:500-1:5000; IHC: Human Heart Tissue, 1:20-1:200; IF: Hela Cells, 1:10-1:100; IP: Mouse Brain Tissue, 1:200-1:2000; FC: HeLa Cells, N/A
Type: Primary
Antigen: TOM70
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat