Anti-CYP17A1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-498EA 402 USD
Anti-CYP17A1 Rabbit Polyclonal Antibody
The human cytochrome P450c17 enzyme is encoded by the CYP17A1 gene. It is the qualitative regulator of steroidogenesis in the human adrenals.In its absence, aldosterone is produced in the human adrenal zona glomerulosa .The CYP17A1 gene is expressed in the adrenal cortex and the gonads but not in the placenta . Although CYP17A1 has been shown to be a 50-kDa protein, the presence of a lower molecular mass(30 kDa) immunoreactive form in rat Ley- dig cells was previously shown and it is either a degradation product or a truncated form of the 50 kDa enzyme. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5).

Western Blot: HeLa Cells, 1:200-1:1000; IHC: Human Prostate Cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200

Type: Primary
Antigen: CYP17A1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR