TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa. Western blot analysis showed that TAX1BP1 is expressed as an 86 kDa or a 68 kDa protein.
Western Blot: HEK-293 Cells, 1:200-1:2000
Type: Primary
Antigen: TAX1BP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse