MTMR2(myotubularin-related protein 2) is also named as KIAA1073 and belongs to the non-receptor class myotubularin subfamily, which is characterized by the presence of a phosphatase domain. It may regulate vesicular trafficking in Schwann cells and its reversible phosphorylation represents a critical mechanism for regulating the subcellular localization of MTMR2. Mtmr2 is a 73 kDa protein in its monomeric form and exist as a dimer within cells and the protein re-localizes to membranes in hypo-osmotic settings. Defects in MTMR2 are the cause of Charcot-Marie-Tooth disease type 4B1 (CMT4B1).
Western Blot: Human cerebellum Tissue, 1:500-1:5000
Type: Primary
Antigen: MTMR2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat