Anti-DIAPH3 Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-854EA 537.7 USD
Anti-DIAPH3 Rabbit Polyclonal Antibody
DIAPH3 is also refered as diaphanous-related formin-3 which binds to GTP-bound form of Rho and to profilin, acts in a Rho-dependent manner to recruit profilin to the membrane. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. Seven isoforms of DIAPH3 exist due to the alternative splicing. Recently it has been reported that dimerization and actin assembly activity of DIAPH3 isoforms 1 and 7 are essential for induction of specific cell protrusions. It may propose that isoform-selective actin assembly by DIAPH3 exerts specific and differentially regulated functions during cell adhesion and motility.

Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human cervical cancer Tissue, 1:20-1:200

Type: Primary
Antigen: DIAPH3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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