Anti-ADAR Rabbit Polyclonal Antibody

Supplier: Proteintech
10082-502EA 537.7 USD
Anti-ADAR Rabbit Polyclonal Antibody
ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region. The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon (IFN) inducible ∼150 kDa protein and a constitutively expressed N-terminally truncated ∼110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters. It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities.

Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human gliomas Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200; IP:Y79 Cells, 1:200-1:2000

Type: Primary
Antigen: ADAR
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Pig
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