Anti-IRF9 Rabbit Polyclonal Antibody

Supplier: Proteintech
14167-1-AP-150UL
10088-978EA 537.7 USD
10088-978
Anti-IRF9 Rabbit Polyclonal Antibody
Antibodies
Interferon regulatory factor 9 (IRF9) also named Interferon-stimulated gene factor 3 gamma (ISGF3) is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Western Blot: Mouse Heart Tissue, 1:200-1:2000; IHC: Human cervical cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200

Type: Primary
Antigen: IRF9
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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