Anti-ELAVL2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10086-462EA 402 USD
Anti-ELAVL2 Rabbit Polyclonal Antibody
The ELAV (embryonic lethal abnormal visual system) gene of D. Melanogaste is the the first identified member of a family of neuronal RNA binding proteins that is conserved in metazoans. The proteins in this family contain three RNA Recognition Motifs (RRM), with a hinge region separating the second and third RRMs and an optional non-conserved N-terminal region. The hinge includes signals essential for nuclear export and subcellular localization . Elav is expressed specifically in the neurons and is required for the correct development and maintenance of the nervous system. ELAVL2 can binds RNA, and recognize a GAAA motif. In addition, it can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.

Western Blot: Mouse cerebellum Tissue, 1:1000-1:10000; IHC: Human Brain, 1:20-1:200

Type: Primary
Antigen: ELAVL2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, zebrafish
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