Anti-MAPKAPK2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10089-964EA 402 USD
Anti-MAPKAPK2 Rabbit Polyclonal Antibody
MAPKAPK2(mitogen-activated protein kinase-activated protein kinase 2) is also named as MK2, MAPKAP-K2, MK-2 and belongs to the CAMK Ser/Thr protein kinase family. MAPKAPK2, one of several kinases directly phosphorylated and activated by p38 MAPK, plays a central role in the inflammatory response and is in the nucleus of unstimulated cells and moves rapidly to the cytoplasm after stimulation. It is also involved in many other cellular processes including stress responses, nuclear export, gene expression regulation and cell proliferation. Multiple residues of MAPKAPK2 are generally phosphorylated in vivo in response to stress, but only 4 residues(Thr25, Thr222, Ser272, and Thr334) are phosphorylated by p38 MAPK in vitro. It has 2 isoforms produced by alternative splicing and the range of the molecular weight is 42-60 kDa according to the references.

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human Kidney Tissue, 1:20-1:200

Type: Primary
Antigen: MAPKAPK2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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