Anti-CX3CR1 Rabbit Polyclonal Antibody

Supplier: Proteintech
13885-1-AP-150UL
10085-370EA 537.7 USD
10085-370
Anti-CX3CR1 Rabbit Polyclonal Antibody
Antibodies
CX3CR1, also known as GPR13, V28 and fractalkine receptor, belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).

Western Blot: HL-60 Cells, 1:200-1:2000; IHC: Human tonsillitis Tissue, 1:20-1:200

Type: Primary
Antigen: CX3CR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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