PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.
Western Blot: Mouse Thymus Tissue, 1:500-1:5000; IHC: Human Liver cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200; IP: HEK-293 Cells, 1:500-1:5000
Type: Primary
Antigen: PFKFB3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat