Anti-GMFG Rabbit Polyclonal Antibody

Supplier: Proteintech
10087-664EA 402 USD
Anti-GMFG Rabbit Polyclonal Antibody
GMFG (glia maturation factor-γ), is a 17 kDa protein that belongs to the GMF subfamily of the larger Actin-binding protein ADF family. In adult rat, the GMFG mRNA is predominantly expressed in the thymus, testis, and lung. GMFG is considered a hematopoietic-specific protein that may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG has several serine/threonine (Ser/Thr) phosphorylation sites, and can be phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac1 and Cdc42. Expression of GMFG enhances actin-based cellular functions such as migration and tube-formation in endothelial cells. GMFG expression is also significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively.

Western Blot: Human Placenta Tissue, 1:200-1:2000; IHC: Human lung cancer Tissue, 1:20-1:200

Type: Primary
Antigen: GMFG
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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