Anti-MLXIP Rabbit Polyclonal Antibody

Supplier: Proteintech
10090-286EA 537.7 USD
Anti-MLXIP Rabbit Polyclonal Antibody
Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP.

Western Blot:K-562 Cells, 1:500-1:5000; IHC: Human Skeletal Muscle, 1:20-1:200

Type: Primary
Antigen: MLXIP
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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