Anti-BST2 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

Anti-BST2 Rabbit Polyclonal Antibody

13560-1-AP-150UL

10083-704EA 402 USD

10083-704

Anti-BST2 Rabbit Polyclonal Antibody

Antibodies

BST2, also named as CD317 and Tetherin, belongs to the tetherin family. It may be involved in the sorting of secreted proteins and it is involved in pre-B-cell growth. BST2 is an antiretroviral defense protein, that blocks release of retrovirus from the cell surface. Depleted unpon HIV-1 infection by viral VPU protein through 20S proteasome degradation. Depleted upon infection by human Kaposi's sarcoma-associated herpesvirus (KSHV) through ubiquitination and subsequent degradation. BST2 may play a role in B-cell activation in rheumatoid arthritis. It is recently identified interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses, respectively. BST2 is a plasma membrane proteins, tetherin inhibits virion particle release from infected cells. BST2 is effective against retroviruses and flavoviruses whilst IFITMs disrupt influenza and flavivirus infection.

Western Blot: Human Heart Tissue, 1:500-1:5000; IHC: Human Liver Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200; FC: HepG2 Cells, N/A

Type: Primary
Antigen: BST2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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