Beta-2-microglobulin (B2M, 12 kDa) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.
Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human oesophagus cancer Tissue, 1:20-1:200; FC: HeLa Cells, N/A
Type: Primary
Antigen: B2M
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse