Mediator of RNA polymerase II transcription subunit 19 (MED19) is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II . Mediator complex is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors . MED19 may be a novel proliferation regulator that promotes lung cancer and gastric cancer progression and cellular growth .
Western Blot: Human Testis Tissue, 1:200-1:1000; IHC: Human Testis Tissue, 1:20-1:200
Type: Primary
Antigen: MED19
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat