Anti-HSPH1 Rabbit Polyclonal AntibodySupplier: Proteintech
10087-638EA 402 USD10087-638
Anti-HSPH1 Rabbit Polyclonal Antibody
HSP105, also known as HSP110 or HSPH1, belongs to the heat shock protein (HSP) family. Human HSP105 is a high-molecular-weight chaperone protein expressed at constitutively low levels as a cytoplasmic α-isoform and as an inducible nuclear β-isoform on exposure to various forms of stress. HSP105 is constitutively overexpressed in several solid tumors, including melanoma, breast, thyroid, and gastroenteric cancers, and exerts antiapoptotic functions. Recently HSP105 has been identified as a novel candidate biomarker of lymphoma aggressiveness. This antibody recognizes both HSP105α and HSP105β isoforms. Western blot analysis using this antibody detected a major band around 100-110kD in Jurkat cells.
Western Blot: MCF7 Cells, 1:500-1:5000; IF: Hela Cells, 1:20-1:200; IHC: Human Testis Tissue, 1:20-1:200
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