Anti-MCM6 Rabbit Polyclonal Antibody

Supplier: Proteintech
10090-050EA 402 USD
Anti-MCM6 Rabbit Polyclonal Antibody
The MCM genes were firstly identified in yeast defective in minichromosome maintenance and have since been shown to have roles in the progression of the cell cycle, and most of them are cell division control genes. MCM2-7 complex are suggested to be 'DNA licensing factors' which bind to the DNA after mitosis and enable DNA replication before being removed during S phase. Mini-chromosome maintenance 6 (MCM6) is one component of the MCM2-7 complex which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. MCM6 single subunit forms homohexamer and contains an ATP-dependent and replication fork stimulated 3' to 5' DNA unwinding activity along with intrinsic DNA-dependent ATPase and ATP-binding activities .

Western Blot: Mouse Testis Tissue, 1:500-1:5000; IHC: Human cervical cancer Tissue, 1:20-1:200; IP: HeLa Cells, 1:500-1:5000

Type: Primary
Antigen: MCM6
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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